FIGURE

Fig. 4

ID

ZDB-FIG-130828-15

Publication

Zhao et al., 2013 - Reptin/Ruvbl2 is a Lrrc6/Seahorse interactor essential for cilia motility

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Fig. 4

reptin^hi2394 mutants show cilia-independent phenotypes. (A) Sections of the eye at 5 dpf. RPE, retinal pigment epithelium; OS, outer segment; ONL, outer nuclear layer; OPL, outer plexiform layer; INL, inner nuclear layer. (Scale bar, 20 μm.) (B–E) The head and eye region at 2-dpf mutants stained with an anti-γH2AX antibody in red. The boxed regions (Left) of B–E are magnified on corresponding Right. The pair of bright red circles in each image is the pair of lenses. (Scale bar, 100 μm.) WT, wild type; ift172, ift172^hi2211 mutant; sea, seahorse^hi3308 mutant; rep, reptin^hi2394 mutant.

Expression Data

Gene:	h2ax
Antibody:	Ab1-h2afx
Fish:	WT dnaaf11^{hi3308Tg/hi3308Tg} ift172^{hi2211Tg/hi2211Tg} ruvbl2^{hi2394Tg/hi2394Tg}
Anatomical Term:	brain
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dnaaf11^{hi3308Tg/hi3308Tg} ift172^{hi2211Tg/hi2211Tg} ruvbl2^{hi2394Tg/hi2394Tg}
Observed In:	brain DNA damage response photoreceptor outer segment layer retina
Stage Range:	Long-pec to Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA