FIGURE

Fig. S3

ID

ZDB-FIG-130726-46

Publication

Melvin et al., 2013 - A morpholino-based screen to identify novel genes involved in craniofacial morphogenesis

Other Figures

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Fig. S3

Cartilage rotation and fusion defects in meis1 and meis2a morphants. A, Ventral view of viscerocranial cartilages of a 5dpf uninjected larva. A′, Magnified view of A showing position of palatoquadrate (arrowhead). B, Ventral view of viscerocranial cartilages of a 5dpf meis1 ATG morphant larva. B′, Magnified view of B showing cartilage fusions in morphants as well as an apparent rotation of the palatoquadrate cartilage (arrowhead). C, Ventral view of viscerocranial cartilages of a 5pf morphant larva co-injected with both meis1 ATG and meis1 SPL MOs. C′, Magnified view of C showing cartilage fusions in morphants and the apparent rotation of the palatoquadrate cartilage (arrowhead). D, Ventral view of viscerocranial cartilages of a 5dpf meis2a ATG morphant larva. D′, Magnified view of D showing cartilage fusions (asterisks) in morphants. E, Ventral view of viscerocranial cartilages that were dissected and flat-mounted from a 5dpf meis2a ATG morphant larva showing cartilage fusions (asterisks). Arrow indicates where a cartilage fusion was broken during dissection.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-meis1b WT + MO2-meis1b + MO5-meis1b WT + MO3-meis2a
Knockdown Reagents:	MO2-meis1b MO3-meis2a MO5-meis1b
Observed In:	ceratobranchial cartilage ceratohyal cartilage cranial cartilage hyosymplectic cartilage Meckel's cartilage palatoquadrate cartilage (all 6)
Stage:	Day 5

Phenotype Detail

Acknowledgments

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