FIGURE

Fig. 4

ID

ZDB-FIG-130123-40

Publication

Clanton et al., 2013 - Fgf signaling governs cell fate in the zebrafish pineal complex

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Fig. 4

fgf8a^x15 mutants have a selective increase in cone photoreceptor number compared with WT larvae. (A) Schematic of the pineal complex of the larval zebrafish at 52 hpf. (B-E) Dorsal (B,C) and frontal (D,E) views of WT and fgf8a^x15 mutants labeled with foxd3:GFP (pineal complex) and Arr3a (cone photoreceptors) at 52 hpf. fgf8a^x15 mutants lack a distinct parapineal organ compared with WT (white arrowheads). L, left; R, right. (F,G) fgf8a^x15 and WT embryos have equivalent numbers of foxd3:GFP expressing cells (F), projection neurons (HuC/D) and rod photoreceptors (Opsin1) (G). However, fgf8a^x15 mutants have more cone photoreceptors (Arr3a) in the pineal complex than WT (G) (^**P<0.005 by t-test). Error bars represent s.e.m. Scale bar: 25 μm.

Expression Data

Gene:	GFP
Antibody:	zpr-1
Fish:	zf104Tg fgf8a^x15/x15; zf104Tg
Anatomical Terms:	parapineal organ pineal complex pineal complex photoreceptor cell
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fgf8a^x15/x15; zf104Tg
Observed In:	parapineal organ photoreceptor cell pineal complex
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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