FIGURE

Fig. 2

ID

ZDB-FIG-130123-38

Publication

Clanton et al., 2013 - Fgf signaling governs cell fate in the zebrafish pineal complex

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Loss of Fgf signaling results in fewer parapineal cells. (A,B) Dorsal views of WT and fgf8a^x15 mutant zebrafish embryos labeled with gfi-1.2 (parapineal cells; black arrowheads). (C,D) Dorsal views showing expression of gfi-1.2 (black arrowheads) in WT larvae at 52 hpf that were treated between 24 and 30 hpf with either DMSO or SU5402. In A-D, dashed line encircles the pineal complex anlage. (E) fgf8a^x15 mutants displayed a significant reduction in parapineal cell number compared with WT (^***P=<0.0005 by t-test). (F) Reductions in parapineal cell numbers were observed in embryos treated with SU5402, particularly for 18-24 hpf and 24-30 hpf treatments (^***P<0.0005 by t-test). Error bars represent s.e.m. Scale bar: 25 μm.

Expression Data

Gene:	gfi1ab
Fish:	WT fgf8a^x15/x15
Conditions:	chemical treatment: dimethyl sulfoxide chemical treatment: SU5402
Anatomical Term:	parapineal organ
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT fgf8a^x15/x15
Condition:	chemical treatment: SU5402
Observed In:	cell parapineal organ
Stage Range:	14-19 somites to Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development