FIGURE

Fig. S1

ID

ZDB-FIG-130103-6

Publication

Comyn et al., 2012 - Lack of Developmental Redundancy between Unc45 Proteins in Zebrafish Muscle Development

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Fig. S1

Morphology of 4 dpf unc45 mutants. Wild type siblings (a,a′); unc45a^-/- (b,b); unc45b^-/- (c,c′); and unc45b^-/-; unc45a^-/- (d,d′) mutants. Blood circulates through the hearts of wild type siblings (a,a′) and unc45a^-/- mutants (b,b′) but not in those of the unc45b^-/- mutants (c,c′,d,d′). Cardiac edema is most pronounced in the unc45b^-/- (c,c′) and unc45b^-/-; unc45a^-/- (d,d′) mutants and absent in wild type siblings (arrowheads). A fully inflated swim bladder is present only in wild type embryos, absent in unc45b^-/- and unc45b^-/-; unc45a^-/- mutants, and minimally inflated in unc45a^-/- mutants (arrows). Somite birefringency is reduced in unc45b^/- and unc45b^-/-; unc45a^-/- mutants compared to wild type and unc45a^-/- embryos. Apostrophes following a letter denote an increased magnification of the same embryo.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	unc45a^tr12/tr12 unc45b^sb60/sb60 unc45a^tr12/tr12; unc45b^sb60/sb60
Observed In:	blood circulation pericardium swim bladder
Stage:	Day 4

Phenotype Detail

Acknowledgments

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