ZFIN Image: Comyn et al., 2012, Fig. S1

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Figure Caption

Fig. S1 Morphology of 4 dpf unc45 mutants. Wild type siblings (a,a′); unc45a^-/- (b,b); unc45b^-/- (c,c′); and unc45b^-/-; unc45a^-/- (d,d′) mutants. Blood circulates through the hearts of wild type siblings (a,a′) and unc45a^-/- mutants (b,b′) but not in those of the unc45b^-/- mutants (c,c′,d,d′). Cardiac edema is most pronounced in the unc45b^-/- (c,c′) and unc45b^-/-; unc45a^-/- (d,d′) mutants and absent in wild type siblings (arrowheads). A fully inflated swim bladder is present only in wild type embryos, absent in unc45b^-/- and unc45b^-/-; unc45a^-/- mutants, and minimally inflated in unc45a^-/- mutants (arrows). Somite birefringency is reduced in unc45b^/- and unc45b^-/-; unc45a^-/- mutants compared to wild type and unc45a^-/- embryos. Apostrophes following a letter denote an increased magnification of the same embryo.

Acknowledgments

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