FIGURE

Fig. 6

ID

ZDB-FIG-120316-107

Publication

Kirchmaier et al., 2012 - The Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development

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Fig. 6

The craniofacial skeletal muscles in popdc2 morphants exhibit an abnormal morphology. Confocal analysis of heads of 3 dpf Tg(acta:GFP) embryos, which were injected with (A,C) MO-control (MO-CTR) or MO1/MO2-popdc2 morpholinos, respectively. In the morphants craniofacial muscles are malformed and in many cases significantly reduced in size. Abbreviations: ah, adductor hyoideus; am, adductor mandibulae; ao, adductor operculi; do, dilator operculi; hh, hyohyoideus; ih, interhyoideus; ima, intermandibularis anterior; imp, intermandibularis posterior; io, inferior oblique; ir, interior rectus, lap, levator arcus palatini; mr, medial rectus; sh, sternohyoideus; so, superior oblique; tv 1–5, transversus ventralis 1–5.Scale bar = 50 μm.

Expression Data

Gene:	GFP
Fish:	zf13Tg zf13Tg + MO1-popdc2 + MO2-popdc2
Knockdown Reagents:	MO1-popdc2 MO2-popdc2
Anatomical Terms:	adductor hyohyoid adductor mandibulae adductor operculi dilatator operculi dorsal oblique extraocular muscle hyohyoideus interhyoideus levator arcus palatini medial rectus sternohyoid ventral intermandibularis anterior ventral intermandibularis posterior ventral oblique extraocular muscle ventral rectus ventral transverse
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	zf13Tg + MO1-popdc2 + MO2-popdc2
Knockdown Reagents:	MO1-popdc2 MO2-popdc2
Observed In:	cephalic musculature
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 363(2), Kirchmaier, B.C., Poon, K.L., Schwerte, T., Huisken, J., Winkler, C., Jungblut, B., Stainier, D.Y., and Brand, T., The Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development, 438-450, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.