FIGURE

Fig. 2

ID

ZDB-FIG-111028-26

Publication

Dalgin et al., 2011 - Zebrafish mnx1 controls cell fate choice in the developing endocrine pancreas

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Fig. 2

Mnx1-deficient embryos have endocrine pancreas defects. (A-F) Confocal images of the dorsal pancreatic bud at 24 hpf. ins (green) and isl1 (red) transcripts were detected by double-fluorescent in situ hybridization (FISH) in control (A-C) or Mnx1 MO1-injected (D-F) zebrafish embryos. Anterior to left. (G) Mean (± s.d.) number of cells positive for insulin (ins) or isl1 (red) in control and mnx1 morphants. ^*, P<0.001 (t-test, two-tailed distribution, Bonferroni correction); control, n=35; Mnx1 MO1, n=50.

Expression Data

Genes:	ins isl1a
Fish:	AB AB + MO1-mnx1
Knockdown Reagent:	MO1-mnx1
Anatomical Terms:	posterior pancreatic bud posterior pancreatic bud pancreatic B cell
Stage:	Prim-5

Expression Detail

Gene	Fish	Conditions	Stage	Anatomy	Assay
ins	AB	control	Prim-5	posterior pancreatic bud pancreatic B cell	ISH
ins	AB + MO1-mnx1	standard conditions	Prim-5	posterior pancreatic bud pancreatic B cell	ISH
isl1a	AB	control	Prim-5	posterior pancreatic bud	ISH
isl1a	AB + MO1-mnx1	standard conditions	Prim-5	posterior pancreatic bud	ISH

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Antibody Labeling

No data available

Phenotype Data

Fish:	AB + MO1-mnx1
Knockdown Reagent:	MO1-mnx1
Observed In:	endocrine pancreas development pancreatic B cell posterior pancreatic bud
Stage:	Prim-5

Phenotype Detail

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