FIGURE

Fig. S3

ID

ZDB-FIG-110823-2

Publication

Mapp et al., 2011 - Zebrafish Prickle1b mediates facial branchiomotor neuron migration via a farnesylation-dependent nuclear activity

Other Figures

All Figure Page

Back to All Figure Page

Fig. S3

pk1b and hmgcrb genetically interact. Embryos from hmgcrb^+/- ; Tg(islet1:GFP) crosses were injected with either H₂O (control), suboptimal or optimal doses of Pk1bMO. Injected embryos were fixed at 48 hpf, immunostained for EphA4, and scored for the extent of FBMN migration, as well as for hmgcrb convergent-extension phenotype. Wild-type siblings were used as controls. Injection of a suboptimal dose of MO increases the proportion of hmgcrb+/? embryos with partial and no migration phenotypes.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-prickle1b + MO2-prickle1b hmgcrb^s617/+; rw0Tg hmgcrb^s617/s617; rw0Tg hmgcrb^s617/+; rw0Tg + MO1-prickle1b + MO2-prickle1b hmgcrb^s617/s617; rw0Tg + MO1-prickle1b + MO2-prickle1b
Knockdown Reagents:	MO1-prickle1b MO2-prickle1b
Observed In:	facial nerve motor nucleus neuron migration
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development