FIGURE

Fig. S3

ID

ZDB-FIG-110712-46

Publication

Mönnich et al., 2011 - A zebrafish model of Roberts syndrome reveals that Esco2 depletion interferes with development by disrupting the cell cycle

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Fig. S3

Some neural crest and developmental markers are expressed in a slightly abnormal pattern in esco2 morphants. A, C, Crestin expression at the 16 somite stage. Crestin expressing cells at the anterior side were more condensed in esco2 morphants (C, arrows) than wild type (A). B, D, Sox10 expression was normal in esco2 morphants at the 15 somite stage (D, compared to wild type in B). E–J, Dlx2a expression at 16 somites was normal in esco2 morphants (H, compared to wild type in E). At 24 hpf expression of dlx2a was slightly reduced in the branchial arches and the forebrain of esco2 morphants (I, compared to F). The close-ups on the forebrain show an abnormal dlx2a distribution in esco2 morphants (J, compared to wild type in G).

Expression Data

Genes:	crestin dlx2a sox10
Fish:	WT WT + MO1-esco2
Knockdown Reagent:	MO1-esco2
Anatomical Terms:	cranial neural crest forebrain neural crest cell pharyngeal arch 3-7
Stage Range:	14-19 somites to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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