FIGURE

Fig. 1

ID

ZDB-FIG-101123-56

Publication

Cruz et al., 2010 - Induction and patterning of trunk and tail neural ectoderm by the homeobox gene eve1 in zebrafish embryos

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Fig. 1

Eve1 overexpression causes anterior truncation, suppression of anterior markers, and induction of posterior markers. Zebrafish embryos were injected with eve1 mRNA (as indicated at the bottom left corner of each panel; Ctrl, uninjected controls). (A–C) Eve1 mRNA injected embryos at 48 hpf showing anterior truncation and progressive loss of posterior patterning. (D–O) In situ hybridization of control and eve1 mRNA-injected embryos at 80% epiboly (lateral views, dorsal to the right, where discernible). Genes analyzed are indicated in the top right corner. Expression of the anterior gene otx2 and epidermal gene p63 was suppressed (D, E; N, O), whereas the expression of hoxb1b was expanded by eve1 overexpression (F, G). Expansion also was observed for sox3, zic2a, and sox31 (H–M).

Expression Data

Genes:	hoxb1b otx2b sox3 sox19b tp63 zic2a
Fish:	WT
Anatomical Terms:	anterior presumptive neural plate ectoderm presumptive neural plate whole organism
Stage:	75%-epiboly

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA