Fig. S8
- ID
- ZDB-FIG-101105-8
- Publication
- Vermot et al., 2009 - Reversing blood flows act through klf2a to ensure normal valvulogenesis in the developing heart
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Expression of notch1b, bmp4, and cmlc2 in control ([A, C, and E], respectively) and klf2a MO-treated ([B, D, and F], respectively) embryos. A strong phenotype after klf2a MO treatment is visible in a minority fraction of embryos treated with klf2a MO, which display immature heart growth (13%, n = 20). In these strongly affected embryos, the heart tube morphology is similar to that observed in conditions were blood flow is suppressed (see [7]); they were not used for flow analysis, qPCR, or for scoring valve morphogenesis at later stages. |