FIGURE

Fig. 5

ID

ZDB-FIG-090622-16

Publication

Miller et al., 2003 - Two endothelin 1 effectors, hand2 and bapx1, pattern ventral pharyngeal cartilage and the jaw joint

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

bapx1 is required for jaw joint expression of chd and gdf5. (A-B) Lateral views of wild-type wholemounted embryos at 56 hpf. (A) In uninjected animals, chd is expressed at the jaw joint (arrow) and (B) this domain appears to be absent in bapx1-MO-injected animals (asterisk). The jaw-closer muscle, the adductor mandibulae, which connects the upper and lower jaw, is present and grossly unaffected in bapx1-MO-injected animals. (C,D) Ventral views of wild-type wholemounted embryos at 78 hpf. (C) In uninjected animals, gdf5 is expressed at the first arch joint (arrows) and (D) these domains are severely downregulated in bapx1-MO-injected animals. Second arch midline expression of gdf5 (arrowheads) is also downregulated in bapx1-MO-injected animals. am, adductor mandibulae; M, Meckel′s; pq, palatoquadrate. Scale bars: 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development