FIGURE

Fig. 3

ID

ZDB-FIG-090622-14

Publication

Miller et al., 2003 - Two endothelin 1 effectors, hand2 and bapx1, pattern ventral pharyngeal cartilage and the jaw joint

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Fig. 3

edn1 function is required for jaw joint bapx1 expression. (A-D) bapx1 expression in wild-type (A,C) and edn1 mutant larvae (B,D). (A,B) Lateral views of 36 hpf embryos, focused on the first arch joint domain (arrow in A). First arch mesenchymal expression of bapx1 is absent in edn1 mutants (B). Cells apposed to the eye and the first pharyngeal pouch express bapx1 in both wild types and mutants. (C,D) Ventral views of 54 hpf embryos. Joint domains (arrows in C,D) are abolished in edn1 mutants, whereas the first and second arch midline domains (white and black arrowheads, respectively, in C and D) are present. Inset (D) shows lateral view of same embryo, showing both midline domains are present. Scale bars: 50 μm.

Expression Data

Gene:	nkx3-2
Fish:	WT edn1^{tf216b/tf216b}
Anatomical Terms:	head pharyngeal arch 1 pharyngeal arch 1 joint pharyngeal arch 1 mesenchyme pharyngeal arch 2
Stage Range:	Prim-25 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	edn1^{tf216b/tf216b}
Observed In:	embryonic viscerocranium morphogenesis pharyngeal arch 1 joint
Stage Range:	Prim-25 to Long-pec

Phenotype Detail

Acknowledgments

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