FIGURE

Fig. 3

ID

ZDB-FIG-090127-22

Publication

Targoff et al., 2008 - Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell number

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Bilateral populations of cardiomyocytes are normal in nkx-deficient embryos. In situ hybridization depicts expression of cmlc2 (A,B) and vmhc (C,D) in wild-type (A,C) and nkx-deficient (B,D) embryos. Embryos viewed dorsally, anterior to the top, at the 18-somite stage. Aside from a mild delay in cardiomyocyte migration toward the midline, nkx-deficient embryos appear to have the same patterns of cmlc2 and vmhc expression as are observed in wild-type embryos.

Expression Data

Genes:	myh7 myl7
Fish:	WT WT + MO1-nkx2.7 + MO2-nkx2.5
Knockdown Reagents:	MO1-nkx2.7 MO2-nkx2.5
Anatomical Term:	heart primordium cardiac muscle cell
Stage:	14-19 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-nkx2.7 + MO2-nkx2.5
Knockdown Reagents:	MO1-nkx2.7 MO2-nkx2.5
Observed In:	muscle cell migration ventricular cardiac muscle cell development
Stage:	14-19 somites

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 322(2), Targoff, K.L., Schell, T., and Yelon, D., Nkx genes regulate heart tube extension and exert differential effects on ventricular and atrial cell number, 314-321, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.