FIGURE

Fig. 3

ID

ZDB-FIG-081205-20

Publication

Snelson et al., 2008 - Formation of the asymmetric pineal complex in zebrafish requires two independently acting transcription factors

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Fig. 3

In flh mutants, parapineal specification is normal, but the pineal organ is reduced in size. All panels are dorsal views of the epithalamus of 4 d larvae. A: Expression of gfi-1 (blue), which is restricted to the parapineal organ (arrowhead), reveals ∼10 left-sided cells in WT and (B) flh larvae. C: In WT larvae, both the parapineal (arrowhead) and pineal express foxd3:gfp (green); many cells of the pineal organ are also labeled by the red-green cone marker Zpr-1 (Fret43) (red), but no parapineal cells are Zpr-1-labeled. D: In flh mutants, the pineal organ is drastically reduced in size, including fewer Zpr-1-labeled cells. As in WT, no Zpr-1-labeled cells are detected in the parapineal. E: At 4 d, lov expression is asymmetric in the habenular nuclei; the habenula adjacent to the parapineal (arrow) expresses lov extensively in WT and (F) flh mutants. Scale bars = 25 μm.

Expression Data

Genes:	gfi1ab GFP kctd12.1
Antibodies:	Ab3-GFP zpr-1
Fish:	AB noto^n1/n1 zf104Tg noto^n1/n1; zf104Tg
Anatomical Terms:	epiphysis habenula parapineal organ
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	noto^n1/n1; zf104Tg
Observed In:	epiphysis pineal gland development
Stage:	Day 4

Phenotype Detail

Acknowledgments

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