FIGURE

Fig. 9

ID

ZDB-FIG-081125-1

Publication

Mei et al., 2008 - C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 9

Fig. 9. C1q-like is essential for defense and survival in response to bacterial infection. (A) C1q-like expression changes detected by Q-RT-PCR at different times after the embryos infected by the pathogen bacterium Aeromonas hydrophila at 24 hpf. The ratio of C1q-like to β-actin in untreated embryos was set to 1 in every stage, and all infected embryos were normalized relative to this value. The data represent mean ± SD of three separate experiments. Hpi means hours post infection. (B) At 24 hpf, the normal control wild-type embryos, the over-expressed C1q-like embryos, and the C1q-like morphant embryos were respectively challenged with the pathogen bacterium Aeromonas hydrophila, and the cumulative mortality were recorded at the indicated times after infection. The data represents mean ± SD of three separate experiments. low asterisk p < 0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-c1ql4l
Knockdown Reagent:	MO1-c1ql4l
Observed In:	defense response to bacterium
Stage Range:	Prim-5 to Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 319(2), Mei, J., Zhang, Q.Y., Li, Z., Lin, S., and Gui, J.F., C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis, 273-284, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.