FIGURE

Fig. 5

ID

ZDB-FIG-080715-6

Publication

Mei et al., 2008 - C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis

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Fig. 5

Developmental effects of C1q-like over-expression and UV exposure on zebrafish embryo development. (A) C1q-like expression changes detected by Q-RT-PCR at different times after the embryo exposure to UV. The ratio of C1q-like to β-actin in untreated embryos was set to 1 in every stage, and all UV treated embryos were normalized relative to this value. The data represent mean ± SD of three separate experiments. *p < 0.05 and **p < 0.01. (B) Normal phenotype of control wild-type embryo (a) and the UV exposed embryo phenotypes revealed by TUNEL assays in wild-type (b), p53 MO (c) and C1q-like mRNA injected (d) embryos. Each picture represents typical result from three experiments (more than 20 embryos in each experiment).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT WT + MO4-tp53
Condition:	ultraviolet light
Knockdown Reagent:	MO4-tp53
Observed In:	tail bud
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 319(2), Mei, J., Zhang, Q.Y., Li, Z., Lin, S., and Gui, J.F., C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis, 273-284, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.