FIGURE

Fig. 6

ID

ZDB-FIG-080411-41

Publication

Yamaguchi et al., 2008 - Mutation of DNA primase causes extensive apoptosis of retinal neurons through the activation of DNA damage checkpoint and tumor suppressor p53

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Fig. 6

Expression of zebrafish prim1, p53 and chk2 genes. (A-D) Expression of prim1. Lateral views of embryos (A-C) and sectioned retina (D). The expression of the prim1 gene is observed in the entire head at 24 hpf (A) and is prominent in the eyes and tectum at 33 hpf (B). At 48 hpf, piy expression is observed mainly in the proliferative zones of the eye and tectum (C-D). (E-H) The expression pattern of p53 is similar to that of prim1. (I-L) The expression pattern of the zebrafish chk2 gene is similar to that of prim1.

Expression Data

Genes:	chek2 prim1 tp53
Fish:	WT
Anatomical Terms:	eye head optic tectum proliferative region
Stage Range:	Prim-5 to Long-pec

Expression Detail

Gene	Fish	Conditions	Stage	Anatomy	Assay
chek2	WT	standard conditions	Prim-5	head	ISH
chek2	WT	standard conditions	Prim-15	eye	ISH
chek2	WT	standard conditions	Prim-15	optic tectum	ISH
chek2	WT	standard conditions	Long-pec	eye	ISH
chek2	WT	standard conditions	Long-pec	optic tectum	ISH
chek2	WT	standard conditions	Long-pec	proliferative region	ISH
prim1	WT	standard conditions	Prim-5	head	ISH
prim1	WT	standard conditions	Prim-15	eye	ISH
prim1	WT	standard conditions	Prim-15	optic tectum	ISH
prim1	WT	standard conditions	Long-pec	eye	ISH

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Phenotype Data

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