FIGURE

Fig. 1

ID

ZDB-FIG-070822-55

Publication

Kloosterman et al., 2007 - Targeted Inhibition of miRNA Maturation with Morpholinos Reveals a Role for miR-375 in Pancreatic Islet Development

Other Figures

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Fig. 1

Morpholinos Targeting the Mature miRNA Deplete the Zebrafish Embryo of Specific miRNAs (A) Northern blot for miR-206 in wild-type and MO miR-206–injected embryos at 24, 48, and 72 hpf. 5S RNA serves as a loading control. (B) In situ analysis of miR-206 and miR-124 expression in different stage embryos after injection of MO miR-206. (C) Effect of a morpholino targeting miR-30c on a silencing assay with miR-30c and a responsive GFP sensor construct. (D) In vivo and in vitro effects of a morpholino on the stability and RNA extraction of a synthetic miR-206 duplex. miR-205 serves as a loading control.

Expression Data

Genes:	mir124 mir206-1
Fish:	WT WT + MO1-mir206-1
Knockdown Reagent:	MO1-mir206-1
Anatomical Terms:	central nervous system post-vent region trunk whole organism
Stage Range:	Prim-5 to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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