FIGURE

Fig. 8

ID

ZDB-FIG-070219-25

Publication

Millimaki et al., 2007 - Zebrafish atoh1 genes: classic proneural activity in the inner ear and regulation by Fgf and Notch

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Fig. 8

Stage-dependent requirements for Fgf. Embryos were treated with DMSO (control) or DMSO plus SU5402 for the indicated time intervals. (A-H) Expression of atoh1a in control and SU5402-treated embryos at 18 hpf (A,B) and 24 hpf (E,F), and expression of atoh1b in control and SU5402-treated embryos at 18 hpf (C,D) and 24 hpf (G,H). (I,J) Expression of atoh1a at 22 hpf in atoh1b morphants treated with DMSO (I) and DMSO and SU5402 (J). (K,L) Pax2 staining of hair cells at 30 hpf in embryos treated with DMSO (K) or DMSO and SU5402 (L). ^*, treatment for K, L from 18-24 hpf. All images are dorsolateral views with anterior to the left. Black arrowheads indicate otic expression. White arrowheads indicate sensory epithelia. Scale bar: 30 μm.

Expression Data

Genes:	atoh1a atoh1b
Fish:	AB AB + MO1-atoh1b
Condition:	chemical treatment: SU5402
Knockdown Reagent:	MO1-atoh1b
Anatomical Term:	otic vesicle
Stage Range:	14-19 somites to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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