Fig. 5
- ID
- ZDB-FIG-060203-20
- Publication
- Cunliffe et al., 2006 - Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS
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Expression of pax6a is up-regulated in the hindbrain of hdac1 mutant embryos. (A–H) Expression of pax6a in hindbrain of (A,C,E,G) wild-type sibling, (B,D,F,H) hdac1 mutant embryos at (A,B) 27 hpf, (C,D,G,H) 35 hpf and (E,F) 51 hpf. Panels A–F show transverse sections through the hindbrain of embryos at the level of rhombomere 5; panels G,H show dorsal views of (G) wild-type and (H) hdac1 mutant hindbrain, demonstrating that expression of pax6a is up-regulated throughout the length of the hindbrain as a consequence of the hdac1 mutation. Particularly strong ectopic expression of pax6a can be seen in dorso-medial and ventro-lateral (arrows in B) territories of rhombomere 5 in the hdac1 mutant hindbrain. |
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| Stage Range: | Prim-5 to Long-pec |
Reprinted from Mechanisms of Development, 123(1), Cunliffe, V.T., and Casaccia-Bonnefil, P., Histone deacetylase 1 is essential for oligodendrocyte specification in the zebrafish CNS, 24-30, Copyright (2006) with permission from Elsevier. Full text @ Mech. Dev.