Search Ontology:
GO: Biological Process

regulatory ncRNA-mediated gene silencing

Term ID
GO:0031047
Synonyms
  • gene silencing by RNA
  • RNA-dependent gene silencing
  • RNA-mediated gene silencing
Definition
A process in which an regulatory non-coding RNA molecule reduces expression of target genes. This can occur pre-transcriptionally by assembly of heterochromatin and prevention of transcription or co- or post-transcriptionally by targeting RNAs for degradation or by interfering with splicing or translation. This process starts once the inhibitory RNA molecule has been transcribed, and includes processing of the RNA such as cleavage, modifications, transport from the nucleus to the cytoplasm, loading onto the RISC complex, and the effect on transcription or translation. 15020054
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
has parts
is a type of
has subtype
negatively regulated by
regulated by
Phenotype
Phenotype caused by Genes