Search Ontology:
GO: Biological Process

RISC complex assembly

Term ID
GO:0070922
Synonyms
  • gene silencing by RNA, small RNA loading onto RISC
  • miRISC assembly
  • miRNA loading onto RISC
  • RISC assembly
  • siRNA loading onto RISC involved in gene silencing by small RNA
  • siRNA loading onto RISC involved in RNA interference
  • small RNA loading onto RISC
Definition
The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing complement complex that mediates gene silencing by small RNA. (5)
References
Ontology
GO: Biological Process    QuickGO    AmiGO
Relationships
is part of
is a type of
Phenotype
Phenotype caused by Genes