serotonin uptake inhibitor

Term ID

CHEBI:50949

Synonyms

serotonin reuptake inhibitor
SSRI

Definition

A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.

References

Wikipedia:Selective_serotonin_reuptake_inhibitor

Ontology

ChEBI ( EBI )

Relationships

is a type of: serotonergic drug

serotonergic drug Show first 5 Terms
inverse has_role: (R)-fluoxetine (R)-fluoxetine hydrochloride (R,R)-tramadol (R,R)-tramadol hydrochloride (S)-fenfluramine ... Show All 45 Terms

(R)-fluoxetine (R)-fluoxetine hydrochloride (R,R)-tramadol (R,R)-tramadol hydrochloride (S)-fenfluramine (S)-fenfluramine hydrochloride (S)-fluoxetine (S)-fluoxetine hydrochloride (S,S)-tramadol (S,S)-tramadol hydrochloride amoxapine chlorphenamine citalopram citalopram hydrobromide clomipramine cocaine desipramine escitalopram hydrobromide fenfluramine fenfluramine hydrochloride fluoxetine fluoxetine hydrochloride fluvoxamine LY-367,265 methadone minaprine N-methylparoxetine nefazodone nefopam nefopam hydrochloride noribogaine olanzapine paroxetine paroxetine hydrochloride paroxetine maleate sertraline sertraline hydrochloride sibutramine tramadol tramadol hydrochloride trazodone trazodone hydrochloride venlafaxine vilazodone vilazodone hydrochloride Show first 5 Terms

Phenotype

Phenotype resulting from serotonin uptake inhibitor

Phenotype where environments contain serotonin uptake inhibitor

Phenotype modified by environments containing serotonin uptake inhibitor

Human Disease / Model Data