LY-367,265

Term ID

CHEBI:183634

Synonyms

1-{2-[4-(6-fluoro-1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]ethyl}-5,6-dihydro-1H,4H-[1,2,5]thiadiazolo[4,3,2-ij]quinoline 2,2-dioxide
1-{2-[4-(6-fluoro-1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]ethyl}-5,6-dihydro-4H-2lambda(6)-[1,2,5]thiadiazolo[4,3,2-ij]quinoline-2,2(1H)-dione
LY 367265
LY-367265
LY367265

Definition

A fluoroindole that is 1H-indole in which the hydrogens at positions 3 and 6 are replaced by 1-[2-(2,2-dioxo-5,6-dihydro-4H-2lambda(6)-[1,2,5]thiadiazolo[4,3,2-ij]quinolin-1(2H)-yl)ethyl]-1,2,3,6-tetrahydropyridin-4-yl and fluoro groups, respectively. It is an inhibitor of the 5-hydroxytryptamine transporter (Ki = 2.3 nM) and an antagonist of 5-hydroxytryptamine(2A) receptor (Ki = 0.81 nM).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: dihydropyridine fluoroindole tertiary amino compound thiadiazoloquinoline

dihydropyridine fluoroindole tertiary amino compound thiadiazoloquinoline Show first 5 Terms
has_role: antidepressant geroprotector serotonergic antagonist serotonin uptake inhibitor

antidepressant geroprotector serotonergic antagonist serotonin uptake inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from LY-367,265

Phenotype where environments contain LY-367,265

Phenotype modified by environments containing LY-367,265

Human Disease Model