Search Ontology:
ChEBI

(S)-fenfluramine hydrochloride

Term ID
CHEBI:59730
Synonyms
  • (+)-(S)-N-ethyl-alpha-methyl-m-(trifluoromethyl)phenethylamine hydrochloride
  • (+)-fenfluramine hydrochloride
  • (2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine hydrochloride
  • (2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-aminium chloride
  • dexfenfluramine HCl
  • dexfenfluramine hydrochloride
  • dextrofenfluramine hydrochloride
Definition
The hydrochloride salt of (S)-fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike the racemate it does not possess catecholamine agonist activity. It was formerly given by mouth in the treatment of obesity, but, like the racemate, was withdrawn wolrdwide following reports of valvular heart defects.
References
  • Beilstein:7114728
  • Beilstein:8165762
  • CAS:3239-45-0
  • DrugBank:DB01191
  • KEGG:D03713
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_part
has_role
Phenotype
Phenotype resulting from (S)-fenfluramine hydrochloride
Phenotype where environments contain (S)-fenfluramine hydrochloride
Phenotype modified by environments containing (S)-fenfluramine hydrochloride
Human Disease / Model Data