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Phenotype Figure Summary
Marker:
daw1
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Bearce
et al.
, 2022
Fig. 1
daw1
b1403/b1403
(AB)
heart tube bilateral symmetry, abnormal
otolith fused with otolith, abnormal
otolith increased amount, abnormal
otolith shape, abnormal
post-vent region curved, abnormal
vertebral column asymmetrically curved, abnormal
vertebral column kinked, abnormal
Fig. 2
daw1
b1403/b1403
(AB)
central canal motile cilium decreased cellular motility, abnormal
post-vent region curved, abnormal
Fig. 3
AB + CRISPR1-daw1 + CRISPR2-daw1 + CRISPR3-daw1 + CRISPR4-daw1 + CRISPR5-daw1
post-vent region curved, abnormal
Fig. S9
daw1
b1422/b1422
(AB)
post-vent region curved, abnormal
Leslie
et al.
, 2022
Fig. 2
daw1
b1403/b1403
(AB)
heart heart looping disrupted, abnormal
Kupffer's vesicle
dand5
expression decreased amount, abnormal
Kupffer's vesicle cilium immobile, abnormal
Gao
et al.
, 2010
Fig. 2
AB + MO1-daw1
, 
AB + MO2-daw1
otic vesicle has extra parts of type otolith, abnormal
otolith mislocalised, abnormal
pericardium edematous, abnormal
post-vent region curved ventral, abnormal
pronephros cystic, abnormal
Fig. 3
AB + MO1-daw1
determination of left/right asymmetry in lateral mesoderm disrupted, abnormal
determination of liver left/right asymmetry disrupted, abnormal
heart looping disrupted, abnormal
heart tube mislocalised radially, abnormal
liver mislocalised radially, abnormal
Fig. 5
AB + MO1-daw1
cilium movement disrupted, abnormal
Kupffer's vesicle axonemal dynein complex decreased amount, abnormal
Kupffer's vesicle axoneme structure, abnormal
Kupffer's vesicle cilium decreased coordination, abnormal
Kupffer's vesicle cilium movement quality, abnormal
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