Gene
daw1
- ID
- ZDB-GENE-050419-255
- Name
- dynein assembly factor with WDR repeat domains 1
- Symbol
- daw1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Involved in axonemal dynein complex assembly; cilium-dependent cell motility; and determination of left/right symmetry. Predicted to localize to cilium. Is expressed in several structures, including Kupffer's vesicle; forerunner cell group; nervous system; neural tube; and solid lens vesicle. Orthologous to human DAW1 (dynein assembly factor with WD repeats 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6904039 (41 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ciliary dyskinesia, primary, 52 | 620570 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | G-protein beta WD-40 repeat | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:R4GDM4
|
418 | |||||
|
UniProtKB:F1RB29
|
415 | |||||
|
UniProtKB:Q1LV15
|
415 |
Interactions and Pathways
No data available
Plasmids
No data available