Publication	Data		Fish	Anatomy
Grabinski et al., 2023	Figure 5		cep290fh297/fh297	retina atf3 expression increased amount, abnormal retina atf5a expression increased amount, abnormal retina cd44a expression increased amount, abnormal retina fosab expression increased amount, abnormal retina il11a expression increased amount, abnormal retina irf9 expression increased amount, abnormal retina jun expression increased amount, abnormal retina mych expression increased amount, abnormal retina myclb expression increased amount, abnormal retina stat1a expression increased amount, abnormal
Fogerty et al., 2022	Fig. 1		cep290fh297/fh297; mi2002Tg ,   cep290fh297/fh297; fl1Tg	retinal outer nuclear layer Muller cell proliferative, abnormal retinal outer nuclear layer stem cell proliferation increased process quality, abnormal retinal rod cell cell population proliferation increased process quality, abnormal retinal rod cell sensory epithelium regeneration increased process quality, abnormal
	Fig. 11		cep290fh297/fh297	retina has extra parts of type microglial cell, abnormal retina has fewer parts of type retinal cone cell, abnormal retinal outer nuclear layer cell population proliferation increased process quality, abnormal
	Fig. 12		cep290fh297/fh297	retinal outer nuclear layer stem cell proliferation increased process quality, abnormal
	Fig. 2		cep290fh297/fh297	retina distal region has extra parts of type microglial cell, abnormal retina microglial cell activation increased process quality, abnormal retina microglial cell elongated, abnormal retina peripheral region has extra parts of type microglial cell, abnormal retinal inner plexiform layer has fewer parts of type microglial cell, abnormal
	Fig. 3		cep290fh297/fh297	Muller cell notch3 expression increased amount, abnormal Muller cell stat3 expression increased amount, abnormal Muller cell yap1 expression increased amount, abnormal retina stat3 expression increased amount, abnormal retina yap1 expression increased amount, abnormal
	Fig. 8		cep290fh297/fh297	retina has fewer parts of type retinal cone cell, abnormal
	Fig. 9		cep290fh297/fh297	retina microglial cell activation increased process quality, abnormal retina peripheral region has extra parts of type microglial cell, abnormal retinal inner nuclear layer cell population proliferation increased process quality, abnormal retinal outer nuclear layer cell population proliferation increased process quality, abnormal
Wang et al., 2022	Fig. 1.		cep290uab18/uab18 (AB)	post-vent region curved ventral, abnormal trunk increased curvature, abnormal vertebral column increased curvature, abnormal vertebral column rotational curvature, abnormal
	Fig. 2.		cep290uab18/uab18 (AB)	vertebral column increased curvature, abnormal vertebral column rotational curvature, abnormal
	Fig. 4.		cep290uab18/uab18 (AB)	retina inflammatory response increased occurrence, abnormal retinal outer nuclear layer cell population proliferation increased occurrence, abnormal
	text only		cep290uab18/uab18 (AB)	female organism female sterile, abnormal male organism male sterile, abnormal
Cardenas-Rodriguez et al., 2021	Fig. 1.		cep290fb208/fb208 (AB/TU) ,   AB/TU + MO7-cep290 ,   AB/TU + MO1-cep290	axis curved ventral, abnormal axis curved, abnormal post-vent region curved ventral, abnormal post-vent region curved, abnormal whole organism cep290 expression absent, abnormal
	Fig. 2.		cep290fb208/fb208 (AB/TU) ,   AB/TU + MO7-cep290	Kupffer's vesicle ciliary base cep290 expression absent, abnormal Kupffer's vesicle cilium decreased length, abnormal peripheral olfactory organ cilium cep290 expression absent, abnormal pronephros cilium cep290 expression absent, abnormal retina layer formation disrupted, abnormal retinal inner plexiform layer cep290 expression absent, abnormal retinal outer plexiform layer cep290 expression absent, abnormal
	Fig. 3.		AB/TU + MO7-cep290 ,   cep290fb208/fb208 (AB/TU)	photoreceptor outer segment layer decreased amount, abnormal photoreceptor outer segment layer decreased length, abnormal photoreceptor outer segment layer disorganized, abnormal photoreceptor outer segment layer photoreceptor connecting cilium accumulation photoreceptor outer segment layer vesicle, abnormal retina layer formation disrupted, abnormal
	Fig. 4.		cep290fb208/fb208 (AB/TU)	axis curved, abnormal axis kinked, abnormal post-vent region curved, abnormal
	Fig. 5.		cep290fb208/fb208 (AB/TU)	eye arl13b expression increased amount, abnormal eye arl3b expression increased amount, abnormal eye unc119a2 expression increased amount, abnormal whole organism arl13b expression increased amount, abnormal whole organism arl3b expression increased amount, abnormal whole organism unc119a2 expression increased amount, abnormal
	Fig. 6.		cep290fb208/fb208 (AB/TU)	kidney unc119a2 expression increased amount, abnormal
	Fig. 7.		AB/TU + MO7-cep290	axis curved ventral, abnormal Kupffer's vesicle cilium decreased length, abnormal photoreceptor outer segment layer decreased length, abnormal post-vent region curved ventral, abnormal
	Fig. S1		AB/TU + MO2-cep290 ,   AB/TU + MO7-cep290 ,   AB/TU + MO1-cep290	axis curved ventral, abnormal central canal cilium decreased length, abnormal heart determination of heart left/right asymmetry process quality, abnormal kidney cystic, abnormal otolith amount, abnormal post-vent region curved ventral, abnormal
Leventea et al., 2021	Fig. 1		cep290sa1383/sa1383	whole organism response to osmotic stress increased process quality, abnormal
	Fig. 2		cep290sa1383/sa1383	lapillus erose, abnormal lapillus otolith mineralization decreased process quality, abnormal otolith malformed, abnormal otolith morphogenesis decreased process quality, abnormal
	Fig. 3		cep290sa1383/sa1383	otolith coch expression decreased amount, abnormal
	Fig. 5		cep290sa1383/sa1383	anterior macula anatomical margin coch expression absent, abnormal posterior macula anatomical margin coch expression absent, abnormal
Wang et al., 2020	Fig. 2		cep290sa1383/sa1383	brain development disrupted, abnormal eye decreased size, abnormal eye morphology, abnormal forebrain ventricle decreased size, abnormal hindbrain hydrocephalic, abnormal midbrain hydrocephalic, abnormal pericardium edematous, abnormal retina layer formation disrupted, abnormal swim bladder aplastic, abnormal tectal ventricle decreased size, abnormal telencephalon morphology, abnormal
	Fig. 3		cep290sa1383/sa1383	detection of light stimulus involved in visual perception process quality, abnormal retina apoptotic process increased occurrence, abnormal
Lessieur et al., 2019	Fig 1		cep290fh297/fh297	post-vent region curved ventral, abnormal post-vent region sigmoid, abnormal retina cep290 expression decreased amount, abnormal swim bladder uninflated, abnormal vertebral column anterior-posterior axis increased curvature, abnormal vertebral column curved lateral, abnormal vertebral column deformed, abnormal
	Fig 10		cep290fh297/fh297	photoreceptor inner segment layer zpr-3 labeling mislocalised, abnormal retinal cone cell cone photoreceptor outer segment decreased amount, abnormal retinal cone cell decreased amount, abnormal
	Fig 11		cep290fh297/fh297	photoreceptor inner segment layer zpr-3 labeling mislocalised, abnormal retinal cone cell cone photoreceptor outer segment decreased amount, abnormal retinal cone cell decreased amount, abnormal
	Fig 2		cep290fh297/fh297	retinal cone cell cone photoreceptor outer segment decreased amount, abnormal retinal cone cell cone photoreceptor outer segment disorganized, abnormal retinal cone cell decreased amount, abnormal retinal outer nuclear layer decreased thickness, abnormal
	Fig 3		cep290fh297/fh297	retinal cone cell cone photoreceptor disc membrane broken, abnormal retinal cone cell cone photoreceptor outer segment decreased amount, abnormal retinal cone cell cone photoreceptor outer segment degenerate, abnormal retinal cone cell cone photoreceptor outer segment disorganized, abnormal retinal outer nuclear layer decreased thickness, abnormal
	Fig 4		cep290fh297/fh297	retinal cone cell cone photoreceptor outer segment decreased amount, abnormal retinal cone cell cone photoreceptor outer segment disorganized, abnormal retinal cone cell decreased amount, abnormal
	Fig 6		cep290fh297/fh297	photoreceptor inner segment layer zpr-3 labeling mislocalised, abnormal retinal cone cell decreased amount, abnormal
	Fig 8		cep290fh297/fh297	retinal inner nuclear layer cell population proliferation increased occurrence, abnormal retinal outer nuclear layer cell population proliferation increased occurrence, abnormal
	Fig 9		cep290fh297/fh297	photoreceptor inner segment layer zpr-3 labeling mislocalised, abnormal retinal cone cell cone photoreceptor outer segment decreased amount, abnormal retinal cone cell decreased amount, abnormal
	text only		cep290fh297/fh297	whole organism sterile, abnormal
Lindstrand et al., 2016	Table S4		WT + MO8-cep290	gastrulation disrupted, abnormal
Slaats et al., 2015	Fig. 1		WT + MO1-cep290	signal transduction in response to DNA damage increased magnitude, abnormal
	Fig. S1		WT + MO1-cep290	brain hydrocephalic, abnormal eye decreased size, abnormal pericardium edematous, abnormal trunk curved ventral, abnormal whole organism dead, abnormal whole organism decreased pigmentation, abnormal
Baye et al., 2011	Fig. 2		WT + MO7-cep290	whole organism curved ventral, abnormal
	Fig. 3		WT + MO7-cep290	Kupffer's vesicle decreased size, abnormal
	Fig. 4		WT + MO7-cep290	photoreceptor outer segment layer disorganized, abnormal visual behavior disrupted, abnormal
	Fig. 6		WT + MO7-cep290	visual behavior disrupted, abnormal
Murga-Zamalloa et al., 2011	Fig. 4		WT + MO1-cep290	brain hydrocephalic, abnormal eye decreased size, abnormal pericardium edematous, abnormal post-vent region curved ventral, abnormal post-vent region increased curvature, abnormal retinal photoreceptor layer lacks all parts of type photoreceptor cell photoreceptor outer segment, abnormal
Gerner et al., 2010	Fig. 2		WT + MO5-cep290	brain hydrocephalic, abnormal renal system cystic, abnormal whole organism anterior-posterior axis increased curvature, abnormal
Schäfer et al., 2008	Fig. 2		WT + MO5-cep290	brain hydrocephalic, abnormal midbrain hindbrain boundary decreased thickness, abnormal whole organism curved ventral, abnormal
	Fig. 3		WT + MO5-cep290	pronephros cystic, abnormal
	Fig. 4		WT + MO5-cep290	pronephros cystic, abnormal
Tobin et al., 2008	Fig. 1		WT + MO4-cep290	kidney edematous, abnormal
Sayer et al., 2006	Fig. 3		WT + MO2-cep290 ,   WT + MO1-cep290	brain decreased mass, abnormal brain infiltrative, abnormal cerebellum development disrupted, abnormal cerebellum organization quality, abnormal cerebellum structural organization disrupted, abnormal cloacal septation disrupted, abnormal eye decreased size, abnormal eye malformed, abnormal fourth ventricle composition, abnormal nervous system development disrupted, abnormal otic vesicle decreased size, abnormal otic vesicle formation disrupted, abnormal pronephric glomerulus cystic, abnormal pronephric tubule cystic, abnormal