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Phenotype Figure Summary
Marker:
gla
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Elsaid
et al.
, 2023
Fig. 2
gla
huh1/huh1
(AB/TU)
distal early tubule mitochondrion area density, abnormal
proximal convoluted tubule mitochondrion decreased circumference, abnormal
proximal convoluted tubule mitochondrion increased area, abnormal
proximal convoluted tubule mitochondrion increased diameter, abnormal
proximal convoluted tubule mitochondrion increased perimeter, abnormal
proximal convoluted tubule mitochondrion morphology, abnormal
Fig. 3
gla
huh1/huh1
(AB/TU)
distal early tubule mitochondrial crista decreased area, abnormal
kidney antioxidant decreased amount, abnormal
proximal convoluted tubule mitochondrial crista decreased area, abnormal
Fig. 4
gla
huh1/huh1
(AB/TU)
kidney Ab1-cd63 labeling decreased distribution, abnormal
kidney Ab3-sod2 labeling decreased distribution, abnormal
Elsaid
et al.
, 2022
Fig. 4
gla
huh1/huh1
(AB/TU)
capillary loop nephron dilated, abnormal
kidney alpha-galactosidase activity decreased process quality, abnormal
renal capsular space decreased thickness, abnormal
renal glomerulus
gla
expression absent, abnormal
renal tubule cytoplasm
gla
expression absent, abnormal
Fig. 5
gla
huh1/huh1
(AB/TU)
blood plasma creatine increased amount, abnormal
podocyte podocyte foot increased width, abnormal
urine protein increased amount, abnormal
Elsaid
et al.
, 2022
Figure 4
gla
huh1/huh1
kidney Ab1-idh3 labeling decreased amount, abnormal
kidney Ab2-ctsb labeling decreased amount, abnormal
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