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Phenotype Figure Summary
Marker:
birc5a
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Ko
et al.
, 2011
Fig. 6
WT + MO1-birc5a
head decreased size, abnormal
neuron apoptotic process increased occurrence, abnormal
neuron differentiation disrupted, abnormal
Fig. 9
WT + MO1-birc5a
G1 to G0 transition disrupted, abnormal
head decreased size, abnormal
neuron differentiation disrupted, abnormal
Delvaeye
et al.
, 2009
Fig. 2
WT + MO1-birc5a
brain decreased size, abnormal
head motor neuron disorganized, abnormal
heart morphology, abnormal
pericardium edematous, abnormal
Fig. 3
la116Tg + MO1-birc5a
, 
y1Tg + MO1-birc5a
aortic arch hypoplastic, abnormal
axial vasculature decreased diameter, abnormal
blood vessel development delayed, abnormal
caudal vein plexus morphology, abnormal
dorsal longitudinal anastomotic vessel morphology, abnormal
intersegmental vessel morphology, abnormal
lateral plate mesoderm angioblastic mesenchymal cell cellular motility, abnormal
pharyngeal arch 3-7 neural crest cell decreased amount, abnormal
Fig. 4
WT + MO1-birc5a
erythrocyte differentiation disrupted, abnormal
nucleate erythrocyte decreased amount, abnormal
Fig. 5
WT + MO1-birc5a
atrioventricular valve amorphous, abnormal
endocardial ring amorphous, abnormal
heart decreased size, abnormal
ventricular myocardium decreased thickness, abnormal
Fig. 6
WT + MO1-birc5a
brain apoptotic, abnormal
caudal vein plexus apoptotic, abnormal
posterior neural tube apoptotic, abnormal
Fig. 7
WT + MO1-birc5a
caudal vein plexus proliferative region decreased functionality, abnormal
cell population proliferation decreased occurrence, abnormal
hemopoiesis decreased occurrence, abnormal
neural tube proliferative region decreased functionality, abnormal
Fig. 8
y1Tg + MO1-birc5a
caudal vein plexus morphology, abnormal
dorsal longitudinal anastomotic vessel morphology, abnormal
intersegmental vessel morphology, abnormal
Milan
et al.
, 2009
text only
birc5a
hi1326Tg
heart necrotic, abnormal
Ma
et al.
, 2007
Fig. 2
WT + MO1-birc5a
, 
WT + MO1-birc5a + MO2-birc5a
, 
WT + MO2-birc5a
eye decreased size, abnormal
head decreased size, abnormal
post-vent region curved, abnormal
Fig. 3
y1Tg + MO1-birc5a + MO2-birc5a
blood vessel development disrupted, abnormal
dorsal longitudinal anastomotic vessel aplastic, abnormal
inner optic circle morphology, abnormal
intersegmental vessel morphology, abnormal
optic vein morphology, abnormal
subintestinal vein aplastic, abnormal
Fig. 4
y1Tg + MO3-birc5a
angiogenesis disrupted, abnormal
text only
WT + MO1-birc5a + MO2-birc5a
, 
y1Tg + MO3-birc5a
axial vasculature apoptotic, abnormal
brain apoptotic, abnormal
eye decreased size, abnormal
head decreased size, abnormal
neural tube apoptotic, abnormal
post-vent region curved, abnormal
Phenotype Annotation (1994-2006)
Fig. for (hi1326)
birc5a
hi1326Tg
brain necrotic, abnormal
whole organism bent, abnormal
Fig. for (hi2111)
birc5a
hi2111Tg
brain necrotic, abnormal
whole organism bent, abnormal
Fig. for (hi3018c)
birc5a
hi3018cTg
brain necrotic, abnormal
whole organism bent, abnormal
Amsterdam
et al.
, 2004
text only
birc5a
hi1326Tg/hi1326Tg
central nervous system necrotic, abnormal
trunk curved dorsal, abnormal
whole organism necrotic, abnormal
whole organism viability, abnormal
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