TALEN

TALEN1-gata6

ID

ZDB-TALEN-210322-2

Name

TALEN1-gata6

Previous Names

None

Target

gata6 (1)

Target Sequence 1

5' - CTTCCTCCCGGCGGATCGGA - 3'

Target Sequence 2

5' - GTTGTGGTGCTCGTCTGACA - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
wcm7	gata6

Expression

Gene expression in Wild Types + TALEN1-gata6

No data available

Phenotype

Phenotype resulting from TALEN1-gata6

No data available

Phenotype of all Fish created by or utilizing TALEN1-gata6

Phenotype	Fish	Conditions	Figures
heart development disrupted, abnormal	gata6^wcm7/wcm7	standard conditions	Fig. 10. , Fig. 11. from Sam et al., 2020
ventricular cardiac muscle cell differentiation decreased process quality, abnormal	gata6^wcm7/wcm7	standard conditions	Fig. 10. from Sam et al., 2020
atrium increased area, abnormal	gata6^wcm7/wcm7	standard conditions	Fig. 8. from Sam et al., 2020
whole organism dead, abnormal	gata6^wcm7/wcm7	standard conditions	text only from Sam et al., 2020
heart ltbp3 expression decreased amount, abnormal	gata6^wcm7/wcm7	standard conditions	Fig. 11. from Sam et al., 2020
atrial cardiac muscle cell differentiation decreased process quality, abnormal	gata6^wcm7/wcm7	standard conditions	Fig. 10. from Sam et al., 2020
cardiac ventricle decreased size, abnormal	gata6^wcm7/wcm7	standard conditions	Fig. 7. from Sam et al., 2020
pericardium edematous, abnormal	gata6^wcm7/wcm7	standard conditions	Fig. 1. from Sam et al., 2020
atrium increased size, abnormal	gata6^wcm7/wcm7; f2Tg; twu34Tg	standard conditions	Fig. 9. from Sam et al., 2020
cardiac ventricle has fewer parts of type cardiac muscle cell, abnormal	gata6^wcm7/wcm7; f2Tg; twu34Tg	standard conditions	Fig. 9. from Sam et al., 2020
heart primordium nkx2.5 expression absent, abnormal	gata5^wcm8/wcm8; gata6^wcm7/+	standard conditions	Fig. 3. from Sam et al., 2020
cardiac muscle cell myl7 expression absent, abnormal	gata5^wcm8/wcm8; gata6^wcm7/+	standard conditions	Fig. 3. from Sam et al., 2020
heart primordium absent, abnormal	gata5^wcm8/wcm8; gata6^wcm7/wcm7	standard conditions	Fig. 3. from Sam et al., 2020
cardiac muscle cell absent, abnormal	gata5^wcm8/wcm8; gata6^wcm7/wcm7	standard conditions	Fig. 3. from Sam et al., 2020
heart tube absent, abnormal	gata5^wcm8/wcm8; gata6^wcm7/wcm7	standard conditions	Fig. 3. from Sam et al., 2020
cardiac muscle cell myl7 expression absent, abnormal	gata5^wcm8/wcm8; gata6^wcm7/wcm7	standard conditions	Fig. 3. from Sam et al., 2020
heart primordium nkx2.5 expression absent, abnormal	gata5^wcm8/wcm8; gata6^wcm7/wcm7	standard conditions	Fig. 3. from Sam et al., 2020
cardiac ventricle decreased size, abnormal	gata6^wcm7/wcm7; gata4^wcm6/+	standard conditions	Fig. 7. from Sam et al., 2020
heart ltbp3 expression decreased amount, abnormal	gata6^wcm7/wcm7; gata4^wcm6/wcm6	standard conditions	Fig. 11. from Sam et al., 2020
cardiac ventricle decreased size, exacerbated	gata6^wcm7/wcm7; gata4^wcm6/wcm6	standard conditions	Fig. 7. from Sam et al., 2020
heart tube decreased thickness, abnormal	gata5^wcm8/+; gata6^wcm7/+; gata4^wcm6/+	standard conditions	Fig. 6. from Sam et al., 2020
heart tube straight, abnormal	gata5^wcm8/+; gata6^wcm7/+; gata4^wcm6/+	standard conditions	Fig. 6. from Sam et al., 2020
heart tube absent, abnormal	gata5^wcm8/+; gata6^wcm7/wcm7; gata4^wcm6/wcm6	standard conditions	Fig. 6. from Sam et al., 2020
heart tube absent, abnormal	gata5^wcm8/wcm8; gata6^wcm7/+; gata4^wcm6/wcm6	standard conditions	Fig. 6. from Sam et al., 2020

Citations