Morpholino

MO1-tet2

ID
ZDB-MRPHLNO-140402-10
Name
MO1-tet2
Previous Names
  • zTET2 MO (1)
Target
Sequence
5' - ATTGCTGGTCTTTTCTGTTTCCAT - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
Translation-blocking MO.
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 1
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO1-tet2
Expressed Gene Anatomy Figures
gata1a Fig. 6,  Fig. 9 from Ge et al., 2014
myb Fig. 6 from Ge et al., 2014
runx1 Fig. 6 from Ge et al., 2014
tal1 Fig. 6 from Ge et al., 2014
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Phenotype
Phenotype resulting from MO1-tet2
Phenotype Fish Figures
broad specificity oxidative DNA demethylase activity disrupted, abnormal AB + MO1-tet2 Fig. 7 from Ge et al., 2014
erythrocyte differentiation disrupted, abnormal AB + MO1-tet2 Fig. 5,  Fig. 9 from Ge et al., 2014
erythroid progenitor cell increased accumulation intermediate cell mass of mesoderm, abnormal AB + MO1-tet2 Fig. 9 from Ge et al., 2014
intermediate cell mass of mesoderm erythroid progenitor cell decreased amount, abnormal AB + MO1-tet2 Fig. 9 from Ge et al., 2014
polychromatophilic erythroblast increased amount, abnormal AB + MO1-tet2 Fig. 9 from Ge et al., 2014
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Phenotype of all Fish created by or utilizing MO1-tet2
Phenotype Fish Conditions Figures
intermediate cell mass of mesoderm erythroid progenitor cell decreased amount, abnormal AB + MO1-tet2 standard conditions Fig. 9 from Ge et al., 2014
primitive hemopoiesis disrupted, abnormal AB + MO1-tet2 standard conditions Fig. 9 from Ge et al., 2014
erythrocyte differentiation disrupted, abnormal AB + MO1-tet2 standard conditions Fig. 5,  Fig. 9 from Ge et al., 2014
broad specificity oxidative DNA demethylase activity disrupted, abnormal AB + MO1-tet2 standard conditions Fig. 7 from Ge et al., 2014
polychromatophilic erythroblast increased amount, abnormal AB + MO1-tet2 standard conditions Fig. 9 from Ge et al., 2014
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Citations
TSV
1 - 3 of 3
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