Morpholino

MO4-disc1

ID

ZDB-MRPHLNO-090825-2

Name

MO4-disc1

Previous Names

Target

Sequence

5' - TGTTTCTGTACCTGATACGGCTGTG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

designed to target the exon 8/intron 8 splice site of the disc1 pre-mRNA, resulting in a truncated protein product

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO4-disc1

Expressed Gene	Anatomy	Figures
foxd3	cranial neural crest	Fig. 3 from Drerup et al., 2009
sox10	cranial neural crest	Fig. 3 from Drerup et al., 2009

Phenotype

Phenotype resulting from MO4-disc1

Phenotype	Fish	Figures
cranial cartilage malformed, abnormal	WT + MO4-disc1	Fig. 2 from Drerup et al., 2009
cranial neural crest increased size, abnormal	WT + MO4-disc1	Fig. 3 from Drerup et al., 2009
neural crest cell migration disrupted, abnormal	WT + MO4-disc1	Fig. 3 from Drerup et al., 2009

Phenotype of all Fish created by or utilizing MO4-disc1

Phenotype	Fish	Conditions	Figures
cranial neural crest increased size, abnormal	WT + MO4-disc1	standard conditions	Fig. 3 from Drerup et al., 2009
cranial cartilage malformed, abnormal	WT + MO4-disc1	standard conditions	Fig. 2 from Drerup et al., 2009
neural crest cell migration disrupted, abnormal	WT + MO4-disc1	standard conditions	Fig. 3 from Drerup et al., 2009

Citations