Morpholino

MO3-disc1

ID
ZDB-MRPHLNO-090825-1
Name
MO3-disc1
Previous Names
  • MOE3 (1)
Target
Sequence
5' - GGACTCGATCTAATGAGAGAAATCA - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
designed for the intron 2/exon 3 splice-acceptor site to alter splicing of the disc1 pre-mRNA, deleting exon 3, which introduces a premature stop site and a severely truncated protein.
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 13
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO3-disc1
Expressed Gene Anatomy Figures
foxd3 Fig. 3 with image,  Fig. 8 with image from Drerup et al., 2009
phox2bb Fig. 2 with image from Culbertson et al., 2011
sox10 Fig. 3 with image from Drerup et al., 2009
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Phenotype
Phenotype resulting from MO3-disc1
Phenotype Fish Figures
cartilage morphogenesis decreased process quality, abnormal WT + MO3-disc1 Fig. 2 with image from Culbertson et al., 2011
ceratobranchial cartilage absent, abnormal WT + MO3-disc1 Fig. 2 with image from Culbertson et al., 2011
ceratohyal cartilage malformed, abnormal WT + MO3-disc1 Fig. 2 with image from Culbertson et al., 2011
cranial cartilage malformed, abnormal WT + MO3-disc1 Fig. 2 with image from Drerup et al., 2009
cranial neural crest increased size, abnormal WT + MO3-disc1 Fig. 3 with image from Drerup et al., 2009
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Phenotype of all Fish created by or utilizing MO3-disc1
Phenotype Fish Conditions Figures
posterior lateral line ganglion glial cell increased amount, abnormal WT + MO3-disc1 standard conditions Fig. 8 with image from Drerup et al., 2009
cranial neural crest increased size, abnormal WT + MO3-disc1 standard conditions Fig. 3 with image from Drerup et al., 2009
cranial cartilage malformed, abnormal WT + MO3-disc1 standard conditions Fig. 2 with image from Drerup et al., 2009
ceratohyal cartilage malformed, abnormal WT + MO3-disc1 standard conditions Fig. 2 with image from Culbertson et al., 2011
ceratobranchial cartilage absent, abnormal WT + MO3-disc1 standard conditions Fig. 2 with image from Culbertson et al., 2011
1 - 5 of 12 Show all
Citations
TSV
1 - 2 of 2
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