Morpholino

MO1-ryr3

ID

ZDB-MRPHLNO-090109-2

Name

MO1-ryr3

Previous Names

None

Target

Sequence

5' - GAGCGGCGTTTTTACTTACAGTCCG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

This is a splice blocking morpholino that targets the exon 1 splice donor site.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-ryr3

Expressed Gene	Anatomy	Figures
etv5b	whole organism	Fig. S5 from Jurynec et al., 2008
ryr3	whole organism	Fig. S5 from Jurynec et al., 2008

Phenotype

Phenotype resulting from MO1-ryr3

Phenotype	Fish	Figures
calcium/calmodulin-dependent protein kinase activity decreased rate, abnormal	WT + MO1-ryr3	Fig. 7 from Francescatto et al., 2010
determination of left/right asymmetry in lateral mesoderm disrupted, abnormal	WT + MO1-ryr3	Fig. 6 from Francescatto et al., 2010
protein autophosphorylation decreased occurrence, abnormal	WT + MO1-ryr3	Fig. 7 from Francescatto et al., 2010
slow muscle cell decreased amount, abnormal	WT + MO1-ryr3	Fig. 3 from Jurynec et al., 2008

Phenotype of all Fish created by or utilizing MO1-ryr3

Phenotype	Fish	Conditions	Figures
protein autophosphorylation decreased occurrence, abnormal	WT + MO1-ryr3	standard conditions	Fig. 7 from Francescatto et al., 2010
calcium/calmodulin-dependent protein kinase activity decreased rate, abnormal	WT + MO1-ryr3	standard conditions	Fig. 7 from Francescatto et al., 2010
slow muscle cell decreased amount, abnormal	WT + MO1-ryr3	standard conditions	Fig. 3 from Jurynec et al., 2008
determination of left/right asymmetry in lateral mesoderm disrupted, abnormal	WT + MO1-ryr3	standard conditions	Fig. 6 from Francescatto et al., 2010
slow muscle cell decreased amount, abnormal	TU + MO1-ryr1a + MO1-ryr3	control	Fig. 1 from Klatt Shaw et al., 2018
slow muscle cell muscle pioneer decreased amount, abnormal	TU + MO1-ryr1a + MO1-ryr3	control	Fig. 1 from Klatt Shaw et al., 2018
fast muscle cell decreased amount, abnormal	TU + MO1-ryr1a + MO1-ryr3	control	Fig. 1 from Klatt Shaw et al., 2018
slow muscle cell decreased amount, abnormal	WT + MO1-ryr1a + MO1-ryr3 + MO2-ryr1a	standard conditions	Fig. 3 from Jurynec et al., 2008
enteric nervous system development decreased occurrence, abnormal	w37Tg + MO1-ryr1a + MO1-ryr3	control	Fig. 4 from Klatt Shaw et al., 2018
dorsal root ganglion decreased amount, abnormal	zc7Tg + MO1-ryr1a + MO1-ryr3	control	Fig. 4 from Klatt Shaw et al., 2018

Citations