ZFIN Image: Wen et al., 2015, Fig. S1

Image

Figure Caption

Fig. S1 Co-localization of sox4a/b with cell specific markers at 72 hpf. (A-B′′) FISH for sox4a and sox4b followed by immunostaining for the ganglion and amacrine cell marker HuC/D. Whereas sox4a did not co-localize with HuC/D (A-A′′), some sox4b-positive cells co-localized with HuC/D (B-B′′, arrows). (C-D′′) FISH for sox4a and sox4b followed by immunostaining for the horizontal cell marker Prox1. Sox4a did not co-localize with Prox1 (C-C′′); however some sox4b-positive cells in the outer half of the INL co-localized with Prox1 (D-D′′, arrows). (E-F′′) FISH for sox4a and sox4b followed by immunostaining for the bipolar cell marker PKC-α. No co-localization with PKC-α was detected. (G-H′′) FISH for sox4a and sox4b was performed in embryos transgenic for gfap:GFP which labels Müller glial cells. No co-localization with Müller cells was observed. All scale bars equal 25 µm. GCL, ganglion cell layer; INL, inner nuclear layer.

Figure Data

Expression / Labeling details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 399(1), Wen, W., Pillai-Kastoori, L., Wilson, S.G., Morris, A.C., Sox4 regulates choroid fissure closure by limiting hedgehog signaling during ocular morphogenesis, 139-53, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.