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Fig. 7 axin1 but not axin1(Q162A) rescues telencephalic defects in Axin1-depleted and in mbl-/- embryos.
(A–H) Representative examples of dlx2 expression in control and Axin1-depleted zebrafish embryos (A–D) and in wildtype and mbl-/- embryos (E–H). (A) control uninjected embryo at 24 hpf, (B) axin1-MO-injected, (C) axin1-MO+xx axin1, (D) axin1-MO+axin1(Q162A), (E) wildtype embryo at 24 hpf, (F) mbl-/-, (G) mbl-/-;+axin1 (H) mbl-/-;+axin1(Q162A). (I) Summary of dlx2 expression data. Arrows indicate areas of reduced or absent dlx2 in the telencephalon.
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