ZFIN Image: Esterberg et al., 2009, Fig. 7

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Figure Caption

Fig. 7 fgfr expression is lost from the otic placode and hindbrain of Dlx3b/4b morphants. erm and fgfr1-3 expression are lost from the otic placode and hindbrain of Dlx3b/4b morphants (B,E,H,K). Brackets in (B,K) depict reduction of erm (B) and fgfr3 (K) staining in the hindbrain. Arrows in (E,H) depict loss of fgfr1 staining (E) from the otic placode and loss of fgfr2 staining (H) from the hindbrain of Dlx3b/4b morphants. erm and fgfr1-3 expression can be restored to the otic placode and hindbrain when cv2 mRNA is ectopically expressed in Dlx3b/4b morphants (C,F,I,L). (A–P) 6 somite embryos; dorsal view with anterior to the top. MHB, midbrain–hindbrain boundary; r1, rhombomere 1; r2, rhombomere 2; r3, rhombomere 3; r4, rhombomere 4; r6, rhombomere 6; op, otic placode.

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Expression / Labeling details

Acknowledgments

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Reprinted from Developmental Biology, 325(1), Esterberg, R., and Fritz, A., dlx3b/4b are required for the formation of the preplacodal region and otic placode through local modulation of BMP activity, 189-199, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.