Gene

sema4c

ID
ZDB-GENE-080303-16
Name
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Symbol
sema4c Nomenclature History
Previous Names
  • sc:d411 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have chemorepellent activity and semaphorin receptor binding activity. Predicted to be involved in several processes, including negative regulation of axon extension involved in axon guidance; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to localize to extracellular space and integral component of plasma membrane. Is expressed in several structures, including axial mesoderm; brain; lens placode; olfactory epithelium; and solid lens vesicle. Orthologous to human SEMA4C (semaphorin 4C).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Sheng et al., 2022
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sema4c Human Ortholog
No data available
Associated With sema4c Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001627 Sema domain
Domain IPR007110 Immunoglobulin-like domain
Domain IPR016201 PSI domain
Family IPR027231 Semaphorin
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Homologous_superfamily IPR036352 Sema domain superfamily
Repeat IPR002165 Plexin repeat
Domain Details Per Protein
Protein Length Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Plexin repeat PSI domain Sema domain Sema domain superfamily Semaphorin WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A4JYS4 863
UniProtKB:F1QF70 863
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sema4c-201 (1) Ensembl 3,297 nt
mRNA sema4c-202 (1) Ensembl 3,075 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-sema4c monoclonal Mouse
  • IHC
1
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations