Gene
sema4c
- ID
- ZDB-GENE-080303-16
- Name
- sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
- Symbol
- sema4c Nomenclature History
- Previous Names
-
- sc:d411 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have chemorepellent activity and semaphorin receptor binding activity. Predicted to be involved in several processes, including negative regulation of axon extension involved in axon guidance; neural crest cell migration; and semaphorin-plexin signaling pathway. Predicted to localize to extracellular space and integral component of plasma membrane. Is expressed in several structures, including axial mesoderm; brain; lens placode; olfactory epithelium; and solid lens vesicle. Orthologous to human SEMA4C (semaphorin 4C).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 10 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d411 (17 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Sheng et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR001627 | Sema domain |
Domain | IPR007110 | Immunoglobulin-like domain |
Domain | IPR016201 | PSI domain |
Family | IPR027231 | Semaphorin |
Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Homologous_superfamily | IPR036352 | Sema domain superfamily |
Repeat | IPR002165 | Plexin repeat |
Domain Details Per Protein
Protein | Length | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Plexin repeat | PSI domain | Sema domain | Sema domain superfamily | Semaphorin | WD40/YVTN repeat-like-containing domain superfamily |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A4JYS4
|
863 | |||||||||
UniProtKB:F1QF70
|
863 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
sema4c-201
(1)
|
Ensembl | 3,297 nt | ||
mRNA |
sema4c-202
(1)
|
Ensembl | 3,075 nt |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-sema4c | monoclonal | Mouse |
|
1 |
Plasmids