Gene
grk1b
- ID
- ZDB-GENE-050417-211
- Name
- G protein-coupled receptor kinase 1 b
- Symbol
- grk1b Nomenclature History
- Previous Names
-
- zgc:112194
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Exhibits rhodopsin kinase activity. Involved in cone photoresponse recovery. Is expressed in epiphysis; eye; retinal cone cell; and retinal photoreceptor layer.
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Chrispell et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000961 | AGC-kinase, C-terminal |
| Domain | IPR016137 | RGS domain |
| Family | IPR000239 | GPCR kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036305 | RGS domain superfamily |
| Homologous_superfamily | IPR044926 | RGS, subdomain 2 |
Domain Details Per Protein
| Protein | Length | AGC-kinase, C-terminal | GPCR kinase | Protein kinase domain | Protein kinase-like domain superfamily | RGS domain | RGS domain superfamily | RGS, subdomain 2 | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PXJ6
|
309 | ||||||||
|
UniProtKB:Q49HN0
|
559 |
Interactions and Pathways
No data available
Plasmids
No data available