Gene
tjp1a
- ID
- ZDB-GENE-031001-2
- Name
- tight junction protein 1a
- Symbol
- tjp1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Involved in pigmentation. Localizes to bicellular tight junction. Is expressed in several structures, including immature eye; nervous system; neural tube; pleuroperitoneal region; and tail bud. Orthologous to human TJP1 (tight junction protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 49 figures from 28 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb817 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000906 | ZU5 domain |
Domain | IPR001452 | SH3 domain |
Domain | IPR001478 | PDZ domain |
Domain | IPR008144 | Guanylate kinase-like domain |
Domain | IPR008145 | Guanylate kinase/L-type calcium channel beta subunit |
Domain | IPR035597 | ZO-1, SH3 domain |
Family | IPR005417 | Tight junction protein ZO |
Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
Protein | Length | Guanylate kinase-like domain | Guanylate kinase/L-type calcium channel beta subunit | PDZ domain | PDZ superfamily | P-loop containing nucleoside triphosphate hydrolase | SH3 domain | SH3-like domain superfamily | Tight junction protein ZO | ZO-1, SH3 domain | ZU5 domain |
---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9QHT2
|
1721 | ||||||||||
UniProtKB:A0A8M2BG85
|
1722 | ||||||||||
UniProtKB:A0A8M3B198
|
1721 | ||||||||||
UniProtKB:A0A8M3B1A2
|
1692 | ||||||||||
UniProtKB:A0A8M3B464
|
1725 | ||||||||||
UniProtKB:A0A8M3AUB4
|
1714 | ||||||||||
UniProtKB:A0A8M3AUA1
|
1733 | ||||||||||
UniProtKB:A0A8M2BG91
|
1712 | ||||||||||
UniProtKB:A0A8M9Q2H7
|
1621 | ||||||||||
UniProtKB:A0A8M3BB27
|
1663 | ||||||||||
UniProtKB:A0A8M3AUA6
|
1659 | ||||||||||
UniProtKB:A0A8M3BB23
|
1734 | ||||||||||
UniProtKB:A0A8M9PPT8
|
1641 | ||||||||||
UniProtKB:A0A8M3B467
|
1647 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
tjp1a-201
(1)
|
Ensembl | 4902 nt | |
mRNA |
tjp1a-202
(1)
|
Havana | 6999 nt | |
mRNA |
tjp1a-203
(1)
|
Havana | 676 nt | |
mRNA |
tjp1a-204
(1)
|
Havana | 612 nt | |
mRNA |
tjp1a-205
(1)
|
Havana | 485 nt | |
mRNA |
tjp1a-206
(1)
|
Havana | 1035 nt | |
mRNA |
tjp1a-207
(1)
|
Havana | 544 nt | |
mRNA |
tjp1a-209
(1)
|
Havana | 206 nt | |
mRNA |
tjp1a-210
(1)
|
Havana | 784 nt | |
mRNA |
tjp1a-211
(1)
|
Ensembl | 5101 nt | |
mRNA |
tjp1a-212
(1)
|
Ensembl | 5074 nt | |
ncRNA |
tjp1a-004
(1)
|
Havana | 751 nt |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-tjp1 | monoclonal | IgG1 , k | Mouse |
|
Life Technologies (Invitrogen)
Thermo Fisher Scientific (Lab Vision) |
228 | |
Ab2-tjp1 | polyclonal | Rabbit |
|
Life Technologies (Invitrogen)
|
24 | ||
Ab5-tjp1a | polyclonal | Rabbit |
|
2 | |||
Ab4-tjp1a | polyclonal | Rabbit |
|
1 |
Plasmids
No data available