Gene
cicb
- ID
- ZDB-GENE-030131-1966
- Name
- capicua transcriptional repressor b
- Symbol
- cicb Nomenclature History
- Previous Names
-
- cic
- wu:fb93c01
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within primitive erythrocyte differentiation. Predicted to be active in nucleus. Is expressed in head and hindbrain neural rod. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 45. Orthologous to human CIC (capicua transcriptional repressor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chen et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Huang et al., 2013
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 45 | Alliance | Intellectual developmental disorder, autosomal dominant 45 | 617600 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cell Cycle and Developmental Transcription Regulators | Domain of unknown function DUF4819 | High mobility group box domain | High mobility group box domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:F1Q6M9
|
2623 | ||||
|
UniProtKB:A0A8M2BKS2
|
1398 | ||||
|
UniProtKB:A0A8M2BKS3
|
2632 |
Interactions and Pathways
No data available
Plasmids
No data available