FIGURE

Fig. 5

ID

ZDB-FIG-241121-29

Publication

Cortés-González et al., 2024 - Homozygosity for a hypomorphic mutation in frizzled class receptor 5 causes syndromic ocular coloboma with microcornea in humans

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Fig. 5

Subcellular localization of zebrafish Fzd5 is not affected by the Pro267Leu mutation. (A-C) Subcellular localization of wt-Fzd5-RFP (magenta, A-B; grey, C) and mi-Fzd5-RFP (magenta, D-E; grey F) in 4hpf embryos injected with the corresponding mRNA. Note the membrane localization of both wt-Fzd5-RFP and mi-Fzd5-RFP (arrowheads in B, E). Embryos were co-labelled with phalloidin-488 to reveal cell outlines (green) and Hoechst to reveal cell nuclei (blue). Scale: 50 μm

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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