FIGURE

Fig. 3

ID

ZDB-FIG-241121-27

Publication

Cortés-González et al., 2024 - Homozygosity for a hypomorphic mutation in frizzled class receptor 5 causes syndromic ocular coloboma with microcornea in humans

Other Figures

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Fig. 3

Fluctuation plot and molecular dynamics simulations (A) Fluctuation plot showing the residue fluctuation profile (RMSF) recorded throughout the simulation after global superposition. (B) Molecular dynamics simulations of the wild-type human FZD5, along with the Pro267Leu and Pro267Arg variants, are shown. Ten representative models from the simulation are depicted in cartoon form, with proline, leucine, and arginine illustrated as red sticks

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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