CNS expression of SRPK3 in human and zebrafish embryos. (A) At Carnegie stage 15 (CS15), immunohistochemistry results showing widespread staining of SRPK3 within the hindbrain (hb). (B) At CS19 postmitotic expression is noted in the forebrain (fb), cerebellum (cb) and medulla (m). (C) At CS23 expression is noted in cerebellum. (B′, C′) High magnification images showing intense staining of choroid plexus (cp) epithelium and expression within the cerebellum (cb), medulla (m), and eye. (D) Spatiotemporal expression of srpk3 in developing zebrafish embryo showing transcripts of srpk3 being present at 24 hpf in the brain, heart, and muscles, and in the brain and retinal layers at 72 hpf. Scale bars: 1 mm for (A–C), 100 μm for (D).
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