FIGURE

Fig. 1

ID

ZDB-FIG-240729-81

Publication

Dernovšek et al., 2024 - Exploration and optimisation of structure-activity relationships of new triazole-based C-terminal Hsp90 inhibitors towards in vivo anticancer potency

Other Figures

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Fig. 1

Structure of the Hsp90 dimer (PDB ID: 7L7J), where the NTD is coloured blue, the MD green and the CTD orange. Representative N-terminal inhibitors include geldanamycin, 17-DMAG and TAS-116 – pimitespib, while C-terminal inhibitors include novobiocin and triazole-based inhibitors A, B and C.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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