FIGURE

FIGURE 7

ID

ZDB-FIG-240306-39

Publication

Camacho-Macorra et al., 2024 - Maternal vgll4a regulates zebrafish epiboly through Yap1 activity

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FIGURE 7

Proposed model for maternal vgll4a contribution to zebrafish epiboly progression. Maternal vgll4a promotes plasma membrane localization of the E-cadherin/β-catenin complex in the amount required for an adequate cohesion among blastomeres. This cohesion threshold allows tissue mechano-sensing and thus yap1-dependent mechano-transduction. Signal transduction impacts on the organization and function of the actomyosin ring, thereby promoting timely epiboly progression. E-cad, E-cadherin; β-cat, β-catenin; F-act, F-actin.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol