FIGURE

Fig. 6

ID

ZDB-FIG-231020-27

Publication

Crouzier et al., 2022 - Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models

Other Figures

Fig. 6

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Fig. 6

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Expression Data

Genes:	ncs1a ncs1b sigmar1 wfs1a wfs1b
Antibodies:	Ab1-ncs1 Ab1-tmbim4
Fish:	WT wfs1a^{sa11465/sa11465}; wfs1b^{sa16422/sa16422}
Anatomical Term:	whole organism
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	wfs1a^{sa11465/sa11465}; wfs1b^{sa16422/sa16422}
Conditions:	altered light dark cycle, chemical treatment by environment: N-{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl}-N-propylpropan-1-amine hydrochloride altered light dark cycle, chemical treatment by environment: 1-phenyl-1-cyclohexanecarboxylic acid 2-(4-morpholinyl)ethyl ester altered light dark cycle, chemical treatment by environment: 1-phenyl-1-cyclohexanecarboxylic acid 2-(4-morpholinyl)ethyl ester altered light dark cycle
Observed In:	swimming behavior whole organism
Stage:	Day 5

Phenotype Detail

Acknowledgments

Full text @ Sci. Transl. Med.